SCHEMBL9049378

SCHEMBL9049378

CCOC(OCC)[C@@H]1CSCN1C(=O)[C@@H]1CCCN1C(=O)[C@H]1CCc2ccccc2C1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 18/20 0.53
F2 P00734 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9050605 1.00 PREP (0.53) PREPF2
SCHEMBL9050198 0.95 PREP (0.55) PREPF2
SCHEMBL9048027 0.90 PREP (0.62) PREPF2
SCHEMBL9049588 0.90 PREP (0.62) PREPF2
SCHEMBL9048441 0.89 F2 (0.51) PREPF2
SCHEMBL9048437 0.89 F2 (0.51) PREPF2
SCHEMBL9050551 0.89 F2 (0.51) PREPF2
SCHEMBL9050560 0.89 F2 (0.51) PREPF2
SCHEMBL9047817 0.87 PREP (0.61) PREP
SCHEMBL9047262 0.87 PREP (0.61) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0536399-B1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARM CO LTD (JP) 1996-01-24 EP disclosed
US-5407950-A Brain disorders, senile dementia ZERIA PHARMACEUTICAL CO., LTD. (JP) 1995-04-18 US disclosed
EP-0536399-A1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1993-04-14 EP disclosed