SCHEMBL9049564

SCHEMBL9049564

N#C[C@@H]1CSCN1C(=O)[C@H]1NCC(=S)C1C(=O)CC1Cc2ccccc2C1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PREP P48147 17/20 0.49
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9051226 0.95 PREP (0.52) PREP
SCHEMBL9050173 0.95 PREP (0.52) PREP
SCHEMBL9049179 0.91 PREP (0.43) PREPDPP4
SCHEMBL9048068 0.89 PREP (0.44) PREPDPP4
SCHEMBL9050422 0.88 PREP (0.47) PREPDPP4
SCHEMBL9051115 0.88 PREP (0.47) PREPDPP4
SCHEMBL9051814 0.86 PREP (0.40) PREPDPP4
SCHEMBL8146761 0.84 PREP (0.59) PREPDPP4
SCHEMBL9049633 0.83 PREP (0.42) PREPDPP4
SCHEMBL9045355 0.83 PREP (0.42) PREPDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0536399-B1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARM CO LTD (JP) 1996-01-24 EP disclosed
US-5407950-A Brain disorders, senile dementia ZERIA PHARMACEUTICAL CO., LTD. (JP) 1995-04-18 US disclosed
EP-0536399-A1 NOVEL ARYLALKANOYLAMINE DERIVATIVE AND DRUG CONTAINING THE SAME ZERIA PHARMACEUTICAL CO., LTD. (JP) 1993-04-14 EP disclosed