Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SNCA | P37840 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193363 | 0.73 | TSHR (0.44) | ALDH1A1MAPTLMNACYP3A4TSHR | |
| SCHEMBL10948979 | 0.69 | CYP1A2 (0.36) | ALDH1A1MAPTLMNAPTGS1DRD3 | |
| SCHEMBL29140377 | 0.67 | KDM4E (0.44) | ALDH1A1LMNACYP3A4TSHRMEN1 | |
| SCHEMBL12813387 | 0.65 | GAA (0.37) | ALDH1A1LMNAPTGS1DRD3SLCO1B3 | |
| SCHEMBL9163519 | 0.63 | TSHR (0.50) | ALDH1A1MAPTTSHRTDP1 | |
| SCHEMBL6896312 | 0.62 | CYP1A2 (0.53) | ALDH1A1MAPTLMNAPTGS1DRD3 | |
| SCHEMBL6896309 | 0.62 | CYP1A2 (0.53) | ALDH1A1MAPTLMNAPTGS1DRD3 | |
| SCHEMBL1105235 | 0.61 | MAPT (0.41) | ALDH1A1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL2247665 | 0.60 | TSHR (0.48) | ALDH1A1MAPTLMNAPTGS1TSHR | |
| SCHEMBL6685549 | 0.60 | RARB (0.38) | ALDH1A1LMNAPTGS1DRD3SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033745-A9 | NOVEL COMPOUNDS USEFUL IN MODULATING GENE EXPRESSION OF RETINOID RESPONSIVE GENES AND/OR HAVING ANTI-AP-1 ACTIVITY | — | 1996-01-18 | — | — | WO | disclosed |