⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316953 | 0.69 | — | — | |
| SCHEMBL5539361 | 0.67 | — | — | |
| SCHEMBL10747404 | 0.67 | — | — | |
| SCHEMBL30129407 | 0.67 | — | — | |
| SCHEMBL7365607 | 0.67 | — | — | |
| SCHEMBL15727067 | 0.67 | — | — | |
| SCHEMBL17419323 | 0.67 | — | — | |
| SCHEMBL28256650 | 0.65 | — | — | |
| SCHEMBL290445 | 0.62 | — | — | |
| SCHEMBL6204683 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474815-B1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | OREAL (FR) | 2022-03-16 | — | — | EP | claimed |
| CN-110776406-B | Novel Friedel-Crafts reaction method and catalyst thereof | 福建永晶科技股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-110267949-A | SGC stimulant | 塞科里昂医疗股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-105814049-B | Fused tricyclic imdazole derivatives as TNF active regulator | UCB生物制药私人有限公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-106459047-A | Imidazo [1,2-a ] pyridines as stimulators of soluble guanylate cyclase for the treatment of cardiovascular diseases | 拜耳医药股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105814049-A | Fused tricyclic imidazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105745215-A | Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof | 拜耳制药股份公司 | 2016-07-06 | — | — | CN | disclosed |
| CN-101685733-A | High-temperature thermal fuse device | THERM O DISC INC | 2010-03-31 | — | — | CN | disclosed |
| EP-0532515-B1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER (US) | 1996-10-23 | — | — | EP | disclosed |