SCHEMBL9050183

SCHEMBL9050183

CC(C)n1cc(N)c(CN(C)C)n1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.38
ADORA1 P30542 3/20 0.38
ADORA3 P0DMS8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505515 0.83 ADORA2A (0.33) ADORA2AADORA1
SCHEMBL2321586 0.78 ADORA2A (0.37) ADORA2AADORA1ADORA3
SCHEMBL9052718 0.75 ADORA2A (0.35) ADORA2AADORA1ADORA3
SCHEMBL9050481 0.73 SMN1; SMN2 (0.34) ADORA2AADORA1ADORA3
SCHEMBL9059097 0.72 ADORA2A (0.36) ADORA2AADORA1ADORA3
SCHEMBL28052586 0.72 ADORA2A (0.43) ADORA2AADORA1ADORA3
SCHEMBL6685170 0.70 ADORA2A (0.42) ADORA2AADORA1ADORA3
SCHEMBL9051482 0.69 ADORA2A (0.31) ADORA2AADORA1ADORA3
SCHEMBL1559316 0.69 ADORA2A (0.41) ADORA2AADORA1ADORA3
SCHEMBL19010802 0.67 ADORA2A (0.51) ADORA2AADORA1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996034591-A1 DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION L'OREAL (FR) 1996-11-07 WO claimed