⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL6427076 | 1.00 | — | — | |
| Fluoride SCHEMBL2789664 | 1.00 | — | — | |
| Fluoride SCHEMBL1893486 | 1.00 | — | — | |
| Fluoride SCHEMBL2779216 | 1.00 | — | — | |
| Fluoride SCHEMBL176810 | 1.00 | — | — | |
| Fluoride SCHEMBL23699791 | 1.00 | — | — | |
| Fluoride SCHEMBL18548777 | 1.00 | — | — | |
| Fluoride SCHEMBL244997 | 1.00 | — | — | |
| Fluoride SCHEMBL16970877 | 1.00 | — | — | |
| Fluoride SCHEMBL17765082 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325271-B | Metal-molybdate and method for producing same | BWXT同位素技术集团有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115916749-A | Substituted 5-hydroxyindole compounds as alpha-1 antitrypsin modulators | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115916748-A | Indole derivatives as alpha-1 antitrypsin modulators for the treatment of alpha-1 antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115867543-A | Solid forms of an APOL1 inhibitor and methods of use thereof | 弗特克斯药品有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115784306-A | Metal-molybdate and method for producing same | BWXT同位素技术集团有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115715292-A | 1H-pyrazolo [4,3-g ] isoquinoline and 1H-pyrazolo [4,3-g ] quinoline derivatives as alpha-1-antitrypsin modulators for the treatment of alpha-1-antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115697969-A | 7-or 8-hydroxy-isoquinoline and 7-or 8-hydroxy-quinoline derivatives as alpha-1 antitrypsin modulators for the treatment of alpha-1 antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-1996035697-A1 | ELECTROCHEMILUMINESCENT METAL CHELATE LABELS AND MEANS FOR DETECTION | IGEN, INC. (US) | 1996-11-14 | — | — | WO | disclosed |