SCHEMBL905035

SCHEMBL905035

CC1(C)c2ccccc2-c2ccc(N(c3ccccc3)c3cc(Br)cc(N(c4ccccc4)c4ccc(F)cc4)c3)cc21

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 7/20 0.38
PGR P06401 2/20 0.34
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL904564 0.94 PDK2 (0.39) PDK2PGR
SCHEMBL904944 0.94 PDK2 (0.39) PDK2PGR
SCHEMBL18090335 0.91 PDK2 (0.39) PDK2PGR
SCHEMBL15906930 0.90 PDK2 (0.38) PDK2PGR
SCHEMBL18090472 0.90 PDK2 (0.38) PDK2
SCHEMBL10053406 0.89 PDK2 (0.36) PDK2PGR
SCHEMBL12469759 0.89 PDK2 (0.36) PDK2
SCHEMBL12469534 0.89 PDK2 (0.36) PDK2
SCHEMBL18052475 0.88 PDK2 (0.42) PDK2PGR
SCHEMBL12006116 0.88 PDK2 (0.35) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012043996-A2 COMPOUND IN WHICH AMINE DERIVATIVE IS SUBSTITUTED WITH FLUORENE, ORGANIC ELECTRONIC DEVICE USING SAME, AND TERMINAL THEREOF 덕산하이메탈(주) (KR) 2012-04-05 WO disclosed