Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220835 | 0.79 | TSHR (0.46) | TSHRTDP1CYP3A4GPR35ALDH1A1 | |
| SCHEMBL146142 | 0.79 | ATM (0.36) | TDP1ATMALDH1A1TTR | |
| SCHEMBL7274798 | 0.78 | TSHR (0.50) | TSHRTDP1CYP3A4GPR35ALDH1A1 | |
| SCHEMBL6263483 | 0.76 | TSHR (0.42) | TSHRTDP1CYP3A4GPR35ALDH1A1 | |
| SCHEMBL27186888 | 0.76 | CYP1A2 (0.36) | TSHRTDP1CYP3A4GPR35ALDH1A1 | |
| SCHEMBL10466261 | 0.73 | GRIN2D (0.39) | TDP1ATMALDH1A1 | |
| SCHEMBL641482 | 0.72 | — | — | |
| SCHEMBL7820196 | 0.72 | HPRT1 (0.49) | TSHRTDP1ALDH1A1ACHEHSD17B10 | |
| SCHEMBL58502 | 0.68 | TSHR (0.48) | TSHRTDP1CYP3A4GPR35ALDH1A1 | |
| SCHEMBL3898476 | 0.67 | TSHR (0.58) | TSHRTDP1CYP3A4GPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684824-A4 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES. | FMC CORP (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0684824-A1 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES | FMC CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994018980-A1 | INSECTICIDAL SUBSTITUTED-2,4-DIAMINOQUINAZOLINES | FMC CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |