Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | KLK7 | P49862 | 2/20 | 0.59 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966718 | 1.00 | FOLH1 (0.62) | FOLH1MAPTKLK7KLK5CPB1 | |
| SCHEMBL439919 | 0.94 | KLK7 (0.61) | FOLH1MAPTKLK7KLK5ITGB3 | |
| SCHEMBL29460388 | 0.94 | KLK7 (0.61) | FOLH1MAPTKLK7KLK5ITGB3 | |
| SCHEMBL439918 | 0.94 | KLK7 (0.61) | FOLH1MAPTKLK7KLK5ITGB3 | |
| SCHEMBL9706024 | 0.93 | KLK7 (0.60) | FOLH1MAPTKLK7KLK5SIRT2 | |
| SCHEMBL440527 | 0.92 | KLK7 (0.59) | FOLH1MAPTKLK7KLK5ITGB3 | |
| SCHEMBL440526 | 0.92 | KLK7 (0.59) | FOLH1MAPTKLK7KLK5ITGB3 | |
| SCHEMBL2401280 | 0.92 | FOLH1 (0.65) | FOLH1MAPTKLK7KLK5CPB1 | |
| SCHEMBL29119136 | 0.92 | SIRT2 (0.59) | FOLH1MAPTKLK7KLK5SIRT2 | |
| SCHEMBL29119131 | 0.92 | SIRT2 (0.59) | FOLH1MAPTKLK7KLK5SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | disclosed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | disclosed |