Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720147 | 0.83 | MAPT (0.58) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL8438235 | 0.83 | MAPT (0.46) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL10980033 | 0.83 | MAPT (0.61) | MAPTTDP1LMNAPOLBCCR6 | |
| Ammonia Solution, Strong SCHEMBL8433967 | 0.82 | MAPT (0.45) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL9282689 | 0.82 | MAPT (0.45) | MAPTTDP1LMNAPOLBCCR6 | |
| Ammonia Solution, Strong SCHEMBL8433971 | 0.82 | MAPT (0.45) | MAPTTDP1LMNAPOLBCCR6 | |
| Ammonia Solution, Strong SCHEMBL8433966 | 0.82 | MAPT (0.45) | MAPTTDP1LMNAPOLBCCR6 | |
| Ammonia Solution, Strong SCHEMBL5720361 | 0.81 | MAPT (0.45) | MAPTTDP1LMNAPOLBCCR6 | |
| Ammonia Solution, Strong SCHEMBL5720368 | 0.81 | MAPT (0.45) | MAPTTDP1LMNAPOLBCCR6 | |
| SCHEMBL11189597 | 0.81 | MAPT (0.61) | MAPTTDP1LMNAPOLBCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033713-A9 | ANTI-INFLAMMATORY COMPOUNDS | — | 1996-03-21 | — | — | WO | disclosed |
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| WO-1995033713-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |