Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053775 | 1.00 | ACE (0.50) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL9052241 | 1.00 | ACE (0.50) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL30663369 | 1.00 | ACE (0.50) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL30885617 | 1.00 | ACE (0.50) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL29511093 | 0.85 | ACE (0.69) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL29476622 | 0.85 | ACE (0.69) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL2544386 | 0.85 | ACE (0.69) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL29516656 | 0.85 | ACE (0.69) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL2544384 | 0.85 | ACE (0.69) | ACENOD1MMEKDM4EMAPT | |
| SCHEMBL28303549 | 0.85 | ACE (0.69) | ACENOD1MMEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040746-A1 | LYSYLOXIDASE INHIBITORS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-12-19 | — | — | WO | claimed |