Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.52 |
| ▸ | PDE5A | O76074 | 6/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MIF | P14174 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205161 | 0.84 | PDE4B (0.53) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL3197550 | 0.84 | PDE4B (0.53) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL3193018 | 0.84 | PDE4B (0.53) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL10809810 | 0.78 | PDE4B (0.51) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL10809812 | 0.78 | PDE4B (0.51) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL3205869 | 0.77 | PDE4B (0.56) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL3196384 | 0.74 | PDE4B (0.54) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL653503 | 0.73 | PDE4B (0.76) | PDE4BPDE5APDE3AADORA2AALDH1A1 | |
| SCHEMBL7294668 | 0.72 | ADORA2A (0.56) | ADORA2AADORA1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7294663 | 0.72 | ADORA2A (0.56) | ADORA2AADORA1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8012673-A | — | — | None | — | — | JP | disclosed |
| JP-H0812673-A | PYRAZOLOPYRIDINEOXOALKYLENOIC ACID DERIVATIVE AND ITS PRODUCTION | KYORIN PHARMACEUT CO LTD | 1996-01-16 | — | — | JP | disclosed |