SCHEMBL905276

SCHEMBL905276

O=CC1=CCOC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30594991 0.98
SCHEMBL6058542 0.67
SCHEMBL277317 0.67
SCHEMBL15178398 0.67 CA1 (0.33)
SCHEMBL12706223 0.63
SCHEMBL194443 0.62
SCHEMBL14752566 0.62
SCHEMBL2240829 0.62
SCHEMBL5308708 0.62
SCHEMBL14863740 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326764-A1 INHIBITORS OF THE MENIN-MLL INTERACTION VITAE PHARMACEUTICALS LLC (US) 2025-10-23 US disclosed
US-20250263412-A1 NON-HYDROXAMATE HDAC6 INHIBITORS AND RELATED METHODS OF USE THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-21 US disclosed
EP-4601746-A1 TRICYCLIC COMPOUNDS AND THEIR USES Novartis AG (CH) 2025-08-20 EP disclosed
US-12312359-B2 Inhibitors of the menin-MLL interaction VITAE PHARMACEUTICALS, LLC (US) 2025-05-27 US disclosed
EP-4543878-A1 N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)- QUINOLINE-4-CARBOXAMIDES Astrazeneca AB (SE) 2025-04-30 EP disclosed
US-12252482-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2025-03-18 US disclosed
WO-2025043148-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2025-02-27 WO disclosed
US-20250011330-A1 Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors LEIDOS BIOMEDICAL RESEARCH INC. 2025-01-09 US disclosed
WO-2024079623-A1 TRICYCLIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2024-04-18 WO disclosed
EP-4308562-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF Novartis AG (CH) 2024-01-24 EP disclosed
US-6395767-B2 ANTIDIABETIC AGENTS; SAXAGLIPTIN BRISTOL-MYERS SQUIBB COMPANY 2002-05-28 US disclosed
US-20020019411-A1 Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method ASTRAZENECA AB (SE) 2002-02-14 US disclosed
WO-2001068603-A2 CYCLOPROPYL-FUSED PYRROLIDINE-BASED INHIBITORS OF DIPEPTIDYL IV, PROCESSES FOR THEIR PREPARATION, AND THEIR USE BRISTOL-MYERS SQUIBB CO. (US) 2001-09-20 WO disclosed
EP-0500653-A4 INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE BIOCRYST INC (US) 1995-08-23 EP disclosed
EP-0561841-B1 METHOD OF PREPARING FORMYLTETRAHYDROPYRANS BASF AG (DE) 1995-08-23 EP disclosed
EP-0561841-A1 METHOD OF PREPARING FORMYLTETRAHYDROPYRANS. BASF AG (DE) 1993-09-29 EP disclosed
EP-0500653-A1 INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE BIOCRYST PHARMACEUTICALS INC. (US) 1992-09-02 EP disclosed
WO-1992010488-A1 METHOD OF PREPARING FORMYLTETRAHYDROPYRANS BASF AKTIENGESELLSCHAFT (DE) 1992-06-25 WO disclosed
WO-1991006548-A1 INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE BIOCRYST, INC. (US) 1991-05-16 WO disclosed
US-5008270-A 2-amino-7-(heterocyclomethyl)-3H,5H-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same BIOCRYST, INC. (US) 1991-04-16 US disclosed