Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863460 | 1.00 | BTK (0.40) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL9053257 | 1.00 | BTK (0.40) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL2183149 | 1.00 | BTK (0.40) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL8561700 | 0.94 | GAA (0.43) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL8562006 | 0.94 | BTK (0.44) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL8563555 | 0.93 | GAA (0.46) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL15886867 | 0.90 | BTK (0.38) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL18399601 | 0.90 | BTK (0.38) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL21191759 | 0.89 | BTK (0.42) | BTKGAAEPHX1EPHX2NFKB1 | |
| SCHEMBL14367716 | 0.89 | BTK (0.39) | BTKGAAEPHX1EPHX2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |