Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044009 | 0.94 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL9044364 | 0.90 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL9043529 | 0.89 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL9046041 | 0.89 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL9044945 | 0.89 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL9044723 | 0.89 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL9044106 | 0.88 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL9045379 | 0.88 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL9046770 | 0.88 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL9044621 | 0.88 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |