Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | RARB | P10826 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053700 | 1.00 | MAPT (0.62) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8402273 | 0.96 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8402286 | 0.96 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8402275 | 0.96 | MAPT (0.60) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10701687 | 0.92 | MAPT (0.59) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9361642 | 0.92 | MAPT (0.59) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850258 | 0.87 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850155 | 0.87 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9723153 | 0.87 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850122 | 0.87 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8143489-A | — | — | None | — | — | JP | disclosed |
| JP-H08143489-A | OPTICALLY ACTIVE COMPOUND HAVING 4-FLUOROALKYL GROUP AND LIQUID CRYSTAL COMPOSITION | DAINIPPON INK & CHEM INC | 1996-06-04 | — | — | JP | disclosed |