⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099338 | 0.74 | — | — | |
| SCHEMBL272050 | 0.74 | — | — | |
| SCHEMBL8991671 | 0.70 | — | — | |
| SCHEMBL3024112 | 0.70 | — | — | |
| SCHEMBL12646454 | 0.67 | — | — | |
| SCHEMBL322610 | 0.67 | — | — | |
| SCHEMBL5975691 | 0.67 | — | — | |
| SCHEMBL19510356 | 0.65 | — | — | |
| Tert-Butanol SCHEMBL1134092 | 0.60 | — | — | |
| Formic Acid SCHEMBL16589400 | 0.60 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330678-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-28 | — | — | US | claimed |
| EP-3846808-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-07-14 | — | — | EP | claimed |
| EP-2960233-B1 | NEW THERAPEUTIC AGENTS | CANCER RESEARCH TECH LTD (GB) | 2019-10-30 | — | — | EP | claimed |
| US-20190048020-A1 | DEUTERIUM-MODIFIED CFTR MODULATORS | CONCERT PHARMACEUTICALS, INC. | 2019-02-14 | — | — | US | claimed |
| CN-106700944-B | A kind of synthetic alkali, A are to sapphire polishing liquid and preparation method thereof | 北京国瑞升科技股份有限公司 | 2018-08-21 | — | — | CN | claimed |
| US-20180118684-A1 | THERAPEUTIC AGENTS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2018-05-03 | — | — | US | claimed |
| CN-106700944-A | Synthetic alkali, A-direction sapphire polishing solution and preparation method thereof | 北京国瑞升科技股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| US-9358222-B2 | Therapeutic agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-06-07 | — | — | US | claimed |
| EP-2960233-A1 | NEW THERAPEUTIC AGENTS | Cancer Research Technology Limited (GB) | 2015-12-30 | — | — | EP | claimed |
| US-8618158-B2 | Therapeutic agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2013-12-31 | — | — | US | claimed |
| EP-1108000-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED AMIDO PHTHALOCYANINE DERIVATIVES AND SUBSTITUTED AMIDO PHTHALOCYANINE DERIVATIVES | Ciba SC Holding AG (CH) | 2001-06-20 | — | — | EP | claimed |
| EP-1108001-A1 | PIGMENT COMPOSITIONS CONTAINING SUBSTITUTED AMIDO PHTHALOCYANINE DERIVATIVES | Ciba SC Holding AG (CH) | 2001-06-20 | — | — | EP | claimed |
| CN-1056140-C | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 2000-09-06 | — | — | CN | claimed |
| WO-2000012633-A1 | PIGMENT COMPOSITIONS CONTAINING SUBSTITUTED AMIDO PHTHALOCYANINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | claimed |
| WO-2000012632-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED AMIDO PHTHALOCYANINE DERIVATIVES AND SUBSTITUTED AMIDO PHTHALOCYANINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-03-09 | — | — | WO | claimed |
| EP-0603001-B1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1998-08-26 | — | — | EP | claimed |
| US-5459148-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1995-10-17 | — | — | US | claimed |
| CN-1095374-A | Biphenyl derivatives, their preparation and they are in the application for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1994-11-23 | — | — | CN | claimed |
| EP-0603001-A1 | Biphenyl derivatives, their preparation and their use for the treatment of hypertension and cardiac disease | SANKYO COMPANY LIMITED (JP) | 1994-06-22 | — | — | EP | claimed |
| EP-0042154-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-15 | — | — | EP | claimed |