Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620856 | 0.87 | KIT (0.44) | GRIN2BKITKDM1AFLT3PDGFRB | |
| SCHEMBL6618297 | 0.87 | PDGFRB (0.44) | GRIN2BKITBRD4KDM1AFLT3 | |
| SCHEMBL6616763 | 0.84 | GRIN2B (0.47) | GRIN2BKITBRD4FLT3PDGFRB | |
| SCHEMBL9060048 | 0.84 | GRIN2B (0.41) | GRIN2BKITBRD4FLT3PDGFRB | |
| SCHEMBL6617367 | 0.83 | PDGFRB (0.44) | KITFLT3PDGFRBPDGFRA | |
| SCHEMBL9059921 | 0.80 | GRIN2B (0.38) | GRIN2BKITBRD4FLT3PDGFRB | |
| SCHEMBL6621978 | 0.79 | PDGFRB (0.45) | GRIN2BKITBRD4FLT3PDGFRB | |
| SCHEMBL9053527 | 0.79 | BRD4 (0.41) | GRIN2BKITBRD4PDGFRBPDGFRA | |
| SCHEMBL6616597 | 0.78 | GRIN2B (0.41) | GRIN2BKITFLT3PDGFRBPDGFRA | |
| SCHEMBL6617433 | 0.77 | PDGFRB (0.45) | KITFLT3PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007658-A1 | PYRAZOLO[3,4-g]QUINOXALINE COMPOUNDS WHICH INHIBIT PDGF RECEPTOR PROTEIN TYROSINE KINASE | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-03-14 | — | — | WO | disclosed |