Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.65 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 16/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054251 | 1.00 | CACNA1F (0.65) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9524061 | 0.88 | CACNA1F (0.83) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6973407 | 0.86 | KCNH2 (0.56) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6973414 | 0.86 | KCNH2 (0.56) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6973421 | 0.86 | KCNH2 (0.56) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6971662 | 0.86 | KCNH2 (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6971683 | 0.86 | KCNH2 (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6982476 | 0.86 | KCNH2 (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6982464 | 0.86 | KCNH2 (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6971668 | 0.86 | KCNH2 (0.54) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996001262-A1 | NOVEL QUINOLINE COMPOUND AND PROCESS FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO., LTD. (KR) | 1996-01-18 | — | — | WO | claimed |
| WO-1996001262-A1 | NOVEL QUINOLINE COMPOUND AND PROCESS FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO., LTD. (KR) | 1996-01-18 | — | — | WO | disclosed |