⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276026 | 1.00 | — | — | |
| SCHEMBL7949338 | 1.00 | — | — | |
| SCHEMBL27935804 | 0.97 | TSHR (0.46) | — | |
| Ethane SCHEMBL5187495 | 0.97 | TSHR (0.46) | — | |
| SCHEMBL30066031 | 0.95 | ACE2 (0.45) | — | |
| SCHEMBL15514538 | 0.91 | ACE2 (0.47) | — | |
| SCHEMBL9146257 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL8009888 | 0.89 | TSHR (0.44) | — | |
| SCHEMBL22501004 | 0.88 | TSHR (0.42) | — | |
| SCHEMBL13011649 | 0.88 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112055712-A | Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2020-12-08 | — | — | CN | claimed |
| US-20080233621-A1 | Method For Producing Alcohol and Carboxylic Acid Having Optical Activity | API CORPORATION (JP) | 2008-09-25 | — | — | US | claimed |
| EP-1712630-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AND CARBOXYLIC ACID | API Corporation (JP) | 2006-10-18 | — | — | EP | claimed |
| CN-115397824-A | Process for preparing COT inhibitor compounds | 吉利德科学公司 | 2022-11-25 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-112055712-A | Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2020-12-08 | — | — | CN | disclosed |
| US-8420810-B2 | Bicyclic heterocyclic compound | Ono Pharmaceutical, Co., Ltd. (JP) | 2013-04-16 | — | — | US | disclosed |
| EP-2278014-A2 | Method for producing alcohol and carboxylic acid having optical activity | API Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |
| EP-2270178-A2 | Method for producing alcohol and carboxylic acid having optical activity | API Corporation (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-20100137318-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2154139-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-20070225519-A1 | Method for the Production of Optically Active 3-Alkyl Carboxylic Acids and the Intermediate Products Thereof | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2007-09-27 | — | — | US | disclosed |
| US-20070225519-A1 | Method for the Production of Optically Active 3-Alkyl Carboxylic Acids and the Intermediate Products Thereof | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2007-09-27 | — | — | US | disclosed |
| US-20070225519-A1 | Method for the Production of Optically Active 3-Alkyl Carboxylic Acids and the Intermediate Products Thereof | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2007-09-27 | — | — | US | disclosed |
| CN-101027278-A | Preparation of beta-amino acids having affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2007-08-29 | — | — | CN | disclosed |
| CN-1950508-A | Process for producing optically active alcohol and carboxylic acid | API CORP (JP) | 2007-04-18 | — | — | CN | disclosed |
| EP-1748975-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 3-ALKYL CARBOXYLIC ACIDS AND THE INTERMEDIATE PRODUCTS THEREOF | Consortium für elektrochemische Industrie GmbH (DE) | 2007-02-07 | — | — | EP | disclosed |
| EP-1712630-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AND CARBOXYLIC ACID | API Corporation (JP) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005115955-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 3-ALKYL CARBOXYLIC ACIDS AND THE INTERMEDIATE PRODUCTS THEREOF | Consortium für elektrochemische Industrie GmbH (DE) | 2005-12-08 | — | — | WO | disclosed |
| WO-2000024358-A2 | SYNTHESIS AND USES OF THIOPENTONE ENANTIOMERS | THE UNIVERSITY OF SYDNEY (AU) | 2000-05-04 | — | — | WO | disclosed |