Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12782281 | 0.88 | MAPT (0.61) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL27335572 | 0.85 | MAPT (0.78) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL11195043 | 0.85 | MAPT (0.78) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL38665415 | 0.85 | MAPT (0.78) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL28374001 | 0.85 | GLA (0.62) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL17064276 | 0.83 | MAPT (0.75) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL30150728 | 0.83 | MAPT (0.75) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL12782515 | 0.82 | KMT2A (0.60) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL31447965 | 0.82 | MAPT (0.70) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL12845374 | 0.81 | HRH3 (0.60) | MAPTKMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |