Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YES1 | P07947 | 2/20 | 0.80 |
| ▸ | KDR | P35968 | 2/20 | 0.80 |
| ▸ | JAK3 | P52333 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056811 | 0.90 | YES1 (0.74) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL8806556 | 0.90 | YES1 (0.64) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL8805746 | 0.89 | YES1 (0.69) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL32932963 | 0.89 | YES1 (1.00) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL21585709 | 0.89 | YES1 (1.00) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL8805948 | 0.86 | YES1 (0.66) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL8805825 | 0.86 | YES1 (0.66) | YES1KDRJAK3LMNAPLA2G4A | |
| SCHEMBL8805633 | 0.82 | YES1 (0.68) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL9054761 | 0.82 | YES1 (0.83) | YES1KDRJAK3LMNATUBB4A | |
| SCHEMBL8805785 | 0.80 | YES1 (0.59) | YES1KDRJAK3TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |