Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.63 |
| ▸ | HTR1B | P28222 | 9/20 | 0.63 |
| ▸ | HTR2A | P28223 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.59 |
| ▸ | HTR3B | O95264 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054954 | 0.95 | HTR1D (0.57) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL9050506 | 0.92 | HTR1D (0.73) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL9053389 | 0.88 | HTR1D (0.62) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL9053761 | 0.86 | HTR1D (0.60) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL9052520 | 0.80 | HTR1D (0.73) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL8545387 | 0.79 | HTR1D (0.76) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL9051034 | 0.79 | HTR1D (0.71) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL8545343 | 0.78 | HTR1D (0.75) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| SCHEMBL6922555 | 0.77 | HTR1D (1.00) | HTR1DHTR1BHTR2AMAPTSLC6A4 | |
| Oxalic Acid SCHEMBL8543879 | 0.77 | HTR1D (0.73) | HTR1DHTR1BHTR2AMAPTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724580-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011243-A1 | BENZANILIDE DERIVATIVES AS 5HT-1D RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | claimed |