⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10296584 | 0.74 | — | — | |
| SCHEMBL2042560 | 0.71 | — | — | |
| SCHEMBL14879922 | 0.67 | — | — | |
| SCHEMBL16718801 | 0.67 | — | — | |
| SCHEMBL10296597 | 0.63 | — | — | |
| SCHEMBL2044984 | 0.59 | — | — | |
| SCHEMBL35514 | 0.59 | — | — | |
| SCHEMBL11224225 | 0.59 | — | — | |
| SCHEMBL43155 | 0.59 | — | — | |
| Phosphine SCHEMBL28003754 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172258-A9 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2011-07-14 | — | — | US | claimed |
| CN-102001916-A | Indene derivatives as pharmaceutical agents | — | 2011-04-06 | — | — | CN | claimed |
| EP-1615866-B1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC (CA) | 2011-02-16 | — | — | EP | claimed |
| US-20100152220-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2010-06-17 | — | — | US | claimed |
| CN-1805915-A | Indene derivatives as pharmaceutically active agents | INFLAZYME PHARM LTD (CA) | 2006-07-19 | — | — | CN | claimed |
| EP-1615866-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | Inflazyme Pharmaceuticals, Ltd. (CA) | 2006-01-18 | — | — | EP | claimed |
| US-20050004086-A1 | Antiinflammatory agents; antiarthritic agents; brain disorders; multiple sclerosis; gout; inflammatory bowel disorders; gastrointestinal disorders; psoriasis; antiallergens; autoimmune disease | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2005-01-06 | — | — | US | claimed |
| WO-2004092100-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2004-10-28 | — | — | WO | claimed |
| EP-3156387-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | Aquinox Pharmaceuticals (Canada) Inc. (CA) | 2017-04-19 | — | — | EP | disclosed |
| US-20150307426-A9 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2015-10-29 | — | — | US | disclosed |
| US-20140371252-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2014-12-18 | — | — | US | disclosed |
| US-8673975-B2 | Indene derivatives as pharmaceutical agents | AQUINOX PHARMACEUTICALS INC. (CA) | 2014-03-18 | — | — | US | disclosed |
| US-20120270901-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2012-10-25 | — | — | US | disclosed |
| US-8084503-B2 | Indene derivatives as pharmaceutical agents | AQUINOX PHARMACEUTICALS INC. (CA) | 2011-12-27 | — | — | US | disclosed |
| US-20100152220-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | AQUINOX PHARMACEUTICALS INC. (CA) | 2010-06-17 | — | — | US | disclosed |
| US-7601874-B2 | Antiinflammatory agents; antiarthritic agents; brain disorders; multiple sclerosis; gout; inflammatory bowel disorders; gastrointestinal disorders; psoriasis; antiallergens; autoimmune disease | AQUINOX PHARMACEUTICALS INC. (CA) | 2009-10-13 | — | — | US | disclosed |
| CN-1805915-A | Indene derivatives as pharmaceutically active agents | INFLAZYME PHARM LTD (CA) | 2006-07-19 | — | — | CN | disclosed |
| EP-1615866-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | Inflazyme Pharmaceuticals, Ltd. (CA) | 2006-01-18 | — | — | EP | disclosed |
| US-20050004086-A1 | Antiinflammatory agents; antiarthritic agents; brain disorders; multiple sclerosis; gout; inflammatory bowel disorders; gastrointestinal disorders; psoriasis; antiallergens; autoimmune disease | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2005-01-06 | — | — | US | disclosed |
| WO-2004092100-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2004-10-28 | — | — | WO | disclosed |