Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28119801 | 0.94 | TSHR (0.74) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| Sulfuric Acid SCHEMBL11689455 | 0.94 | TSHR (0.74) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28466691 | 0.91 | TSHR (0.77) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| Sulfuric Acid SCHEMBL16824111 | 0.90 | TSHR (0.68) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| Sulfuric Acid SCHEMBL17274499 | 0.88 | TSHR (0.65) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28119800 | 0.86 | TSHR (0.63) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28471134 | 0.85 | TSHR (0.74) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL29387794 | 0.84 | — | — | |
| SCHEMBL28253436 | 0.84 | TSHR (1.00) | TSHRTP53ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL75775 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |