Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 3/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8953824 | 1.00 | CHRNA7 (0.33) | CHRNA7KDM4ECHRNA10CHRNA9CHRM2 | |
| Iodide SCHEMBL8780639 | 1.00 | CHRNA7 (0.33) | CHRNA7KDM4ECHRNA10CHRNA9CHRM2 | |
| SCHEMBL575098 | 0.97 | CHRNA7 (0.34) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL19307694 | 0.97 | CHRNA7 (0.34) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL2865219 | 0.97 | CHRNA7 (0.34) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL19307655 | 0.97 | CHRNA7 (0.34) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 | |
| Iodide SCHEMBL8991344 | 0.97 | CHRNA7 (0.34) | CHRNA7CHRNA10CHRNA9 | |
| Bromide SCHEMBL8953751 | 0.93 | CHRNA7 (0.33) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 | |
| Water SCHEMBL10941646 | 0.93 | CHRNA7 (0.33) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 | |
| Water SCHEMBL22772155 | 0.93 | CHRNA7 (0.33) | CHRNA7CHRM2CHRM4CHRM5CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314619-B1 | Epoxy resin mixture | CIBA GEIGY AG (CH) | 1996-07-10 | — | — | EP | disclosed |
| US-4885354-A | Epoxy resin compositions | CIBA-GEIGY CORPORATION (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0314619-A2 | Epoxy resin mixture | CIBA-GEIGY AG (CH) | 1989-05-03 | — | — | EP | disclosed |