SCHEMBL9055537

CCC(=O)N(Cc1cccc2ccccc12)CC(NC(=O)Cc1cncn1Cc1ccc(C#N)cc1)C(C)CCC(C(NC(=O)Cc1cncn1Cc1ccc(C#N)cc1)C(C)CC)N(Cc1cccc2ccccc12)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	FNTA	P49354	13/20	0.41

▸	FNTB	P49356	13/20	0.41

▸	PGGT1B	P53609	6/20	0.41

▸	CYP11B1	P15538	2/20	0.36

▸	CYP11B2	P19099	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9055531	0.91	FNTA (0.47)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL9055548	0.91	FNTA (0.47)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8296917	0.91	FNTA (0.44)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8296916	0.91	FNTA (0.44)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL9051108	0.88	FNTA (0.42)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8390629	0.88	FNTA (0.48)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL607993	0.88	FNTA (0.48)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8392085	0.86	FNTA (0.43)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL8392092	0.86	FNTA (0.43)	FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL9051111	0.86	FNTA (0.45)	FNTAFNTBPGGT1BCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1996039137-A1	INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE	MERCK & CO., INC. (US)	1996-12-12	—	—	WO	disclosed