Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055642 | 1.00 | NR1H4 (0.36) | NR1H4MAOAMAOBHIF1AMTNR1A | |
| SCHEMBL9056334 | 0.90 | HIF1A (0.37) | NR1H4HIF1AKDM4EALDH1A1MAPT | |
| SCHEMBL9056404 | 0.89 | HIF1A (0.35) | NR1H4MAOAMAOBHIF1AMTNR1A | |
| SCHEMBL9056410 | 0.89 | HIF1A (0.35) | NR1H4MAOAMAOBHIF1AMTNR1A | |
| SCHEMBL8772695 | 0.87 | MAOB (0.39) | NR1H4MAOAMAOBHIF1A | |
| SCHEMBL9057286 | 0.87 | MAOB (0.39) | NR1H4MAOAMAOBHIF1A | |
| SCHEMBL9055753 | 0.85 | HIF1A (0.42) | MAOAMAOBHIF1A | |
| SCHEMBL8772917 | 0.85 | HIF1A (0.42) | MAOAMAOBHIF1A | |
| SCHEMBL9057530 | 0.85 | NR1H4 (0.37) | NR1H4HIF1A | |
| SCHEMBL9056021 | 0.84 | HIF1A (0.38) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014305-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-05-17 | — | — | WO | claimed |
| WO-1996014305-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-05-17 | — | — | WO | disclosed |