Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222370 | 1.00 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL8440275 | 0.96 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL4133153 | 0.96 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL31492758 | 0.96 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL13945632 | 0.94 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL31636167 | 0.94 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL31636170 | 0.91 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL4418169 | 0.91 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL6046850 | 0.91 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL11460175 | 0.91 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278399-A2 | Positive-working resist composition | Fujifilm Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |