Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | PGK1 | P00558 | 1/20 | 0.51 |
| ▸ | PGK2 | P07205 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376279 | 0.88 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2BPI4KA | |
| SCHEMBL4376288 | 0.88 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2BPI4KA | |
| SCHEMBL10688350 | 0.88 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2BPI4KA | |
| SCHEMBL4375251 | 0.84 | ADORA2A (0.52) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4375246 | 0.84 | ADORA2A (0.52) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL10684165 | 0.84 | ADORA2A (0.75) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL10684171 | 0.84 | ADORA2A (0.75) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL10680285 | 0.83 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL10680281 | 0.83 | ADORA2A (0.68) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL6322416 | 0.82 | ADORA2A (0.62) | ADORA2AADORA3ADORA1ADORA2BPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002553-A2 | AMINO PURINE-β-D-RIBOFURANURONAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1996-02-01 | — | — | WO | disclosed |