Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056754 | 0.89 | MEN1 (0.47) | MEN1KMT2AMCL1KDM4EL3MBTL1 | |
| SCHEMBL8388167 | 0.84 | MEN1 (0.47) | MEN1KMT2AMCL1KDM4EL3MBTL1 | |
| SCHEMBL8387072 | 0.82 | PTGES2 (0.42) | MEN1KMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL8388094 | 0.81 | MEN1 (0.48) | MEN1KMT2AMCL1KDM4EL3MBTL1 | |
| SCHEMBL8390344 | 0.80 | MCL1 (0.50) | MEN1KMT2AMCL1LMNASMN1; SMN2 | |
| SCHEMBL8388328 | 0.78 | P2RX4 (0.49) | MEN1KMT2AKDM4ELMNANPSR1 | |
| SCHEMBL8386942 | 0.77 | MEN1 (0.52) | MEN1KMT2AMCL1KDM4EL3MBTL1 | |
| SCHEMBL8388825 | 0.76 | MEN1 (0.50) | MEN1KMT2AMCL1KDM4EL3MBTL1 | |
| SCHEMBL8390661 | 0.76 | MEN1 (0.47) | MEN1KMT2AMCL1KDM4EL3MBTL1 | |
| SCHEMBL9056067 | 0.75 | MAPT (0.46) | MEN1KMT2AMCL1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |