SCHEMBL905710

SCHEMBL905710

CCOC(C)OC1CCCC(C)(OC(C)OCC)C(O)/C=C/C(C)C(/C(C)=C/C=C/C(C)CC2OC2C(C)C(CC)OC(C)OCC)OC1=O

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SF3B3 Q15393 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL905623 0.88 SF3B3 (0.49) SF3B3
SCHEMBL905678 0.86 SF3B3 (0.43) SF3B3
SCHEMBL1504885 0.80 SF3B3 (0.57) SF3B3
SCHEMBL905723 0.80 SF3B3 (0.49) SF3B3
SCHEMBL1504944 0.79 SF3B3 (0.46) SF3B3
SCHEMBL1505072 0.78 SF3B3 (0.51) SF3B3
SCHEMBL905687 0.78 SF3B3 (0.45) SF3B3
SCHEMBL1505002 0.77 SF3B3 (0.36) SF3B3
SCHEMBL1504930 0.77 SF3B3 (0.44) SF3B3
SCHEMBL3876416 0.76 SF3B3 (0.44) SF3B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2277880-A1 Macrolides with VEGF transcription suppression activity Eisai R&D Management Co., Ltd. (JP) 2011-01-26 EP disclosed