Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9056311 | 0.98 | MAPK1 (0.48) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| SCHEMBL16853010 | 0.91 | MAPK1 (0.58) | MAPK1HPGDUSP2SMN1; SMN2ESR2 | |
| Hydrochloric Acid SCHEMBL8325606 | 0.89 | MAPK1 (0.57) | MAPK1HPGDUSP2SMN1; SMN2ESR2 | |
| SCHEMBL326544 | 0.83 | MAPK1 (0.50) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| SCHEMBL24177160 | 0.77 | MAPK1 (0.50) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| SCHEMBL16078939 | 0.76 | ESR2 (0.47) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| SCHEMBL13665326 | 0.76 | HPGD (0.46) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7685100 | 0.76 | MAPK1 (0.49) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| SCHEMBL6350119 | 0.75 | USP2 (0.55) | MAPK1HPGDUSP2SMN1; SMN2MEN1 | |
| SCHEMBL14653322 | 0.74 | USP2 (0.53) | MAPK1HPGDUSP2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | disclosed |