Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057920 | 0.82 | HSP90AA1 (0.64) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| Dihydrocatalpol SCHEMBL29500389 | 0.77 | HSP90AA1 (0.64) | HSP90AA1TSHRXDH | |
| SCHEMBL29425769 | 0.77 | HSP90AA1 (0.49) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| SCHEMBL9573582 | 0.75 | HSP90AA1 (0.57) | HSP90AA1KDM4ESMN1; SMN2XDH | |
| SCHEMBL422812 | 0.75 | HSP90AA1 (0.63) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| SCHEMBL9056457 | 0.75 | KDM4E (0.59) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| SCHEMBL9057747 | 0.75 | KDM4E (0.59) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| SCHEMBL29425942 | 0.72 | HSP90AA1 (0.62) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| SCHEMBL29426115 | 0.71 | KDM4E (0.57) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 | |
| SCHEMBL419954 | 0.71 | HSP90AA1 (0.60) | HSP90AA1KDM4EGLACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010408-A1 | CARDIOACTIVE COMPOUNDS ISOLATED FROM WOODY PERENNIALS | THE EXECUTIVE DIRECTOR OF THE WESTERN AUSTRALIAN DEPARTMENT OF CONSERVATION AND LAND MANAGEMENT (AU) | 1996-04-11 | — | — | WO | disclosed |