⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20719906 | 0.75 | TSHR (0.50) | — | |
| SCHEMBL3309607 | 0.74 | — | — | |
| SCHEMBL332238 | 0.73 | — | — | |
| SCHEMBL4122966 | 0.69 | — | — | |
| SCHEMBL5172943 | 0.69 | — | — | |
| SCHEMBL16433894 | 0.69 | — | — | |
| SCHEMBL9063433 | 0.68 | TSHR (0.50) | — | |
| SCHEMBL3477629 | 0.68 | — | — | |
| SCHEMBL9765585 | 0.67 | — | — | |
| SCHEMBL9579001 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425436-B1 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | claimed |
| EP-0493320-B1 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | EP | claimed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | claimed |
| US-5334681-A | High oxygen permeability; resiliency, flexibility; wettability; biocompatibility | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | claimed |
| EP-0493320-A2 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | claimed |
| US-5115056-A | FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | claimed |
| EP-0425436-A2 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | claimed |
| US-5010141-A | Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| EP-0425436-B1 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | disclosed |
| EP-0493320-B1 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | EP | disclosed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| US-5334681-A | High oxygen permeability; resiliency, flexibility; wettability; biocompatibility | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0291452-B1 | Terminal polyvinyl functional macromers, polymers thereof and contact lenses made therefrom | CIBA GEIGY AG (CH) | 1994-06-01 | — | — | EP | disclosed |
| US-5010141-A | Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |
| US-4923906-A | Rigid, gas-permeable polysiloxane contact lenses | CIBA-GEIGY CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| US-4837289-A | CONTACT LENSES | CIBA-GEIGY CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0291452-A2 | Terminal polyvinyl functional macromers, polymers thereof and contact lenses made therefrom | CIBA-GEIGY AG (CH) | 1988-11-17 | — | — | EP | disclosed |
| US-4605712-A | Unsaturated polysiloxanes and polymers thereof | CIBA-GEIGY CORPORATION (US) | 1986-08-12 | — | — | US | disclosed |