Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.94 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.65 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | ACACB | O00763 | 1/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517633 | 0.98 | RECQL (0.91) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL9927461 | 0.98 | RECQL (0.91) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL21444578 | 0.98 | RECQL (0.91) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL15038847 | 0.97 | RECQL (1.00) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL20663584 | 0.97 | RECQL (1.00) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL19884283 | 0.93 | RECQL (0.87) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL15038846 | 0.93 | RECQL (0.87) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL14314483 | 0.93 | RECQL (0.87) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL1909826 | 0.87 | RECQL (0.77) | RECQLPOLBLMNASMN1; SMN2GAA | |
| SCHEMBL11390159 | 0.86 | RECQL (0.75) | RECQLPOLBLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996000729-A2 | PROCESS FOR THE PREPARATION OF AZANORADAMANTANE BENZAMIDES | G.D. SEARLE & CO. (US) | 1996-01-11 | — | — | WO | disclosed |