Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL9058372

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nearest known ligand 0.77

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.77
MAPK1 P28482 2/20 0.77
MEN1 O00255 4/20 0.71
KMT2A Q03164 4/20 0.71
ALDH1A1 P00352 3/20 0.59
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.32
APP P05067 5/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
CASP1 P29466 1/20 0.31
SLCO1B3 Q9NPD5 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL6171 1.00 TSHR (0.77) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL16125 0.96 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL14919 0.96 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL5692208 0.96 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL19915288 0.93 TSHR (0.67) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL3322788 0.93 TSHR (0.67) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9403004 0.90 TSHR (0.62) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL7858578 0.90 MEN1 (0.69) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9043761 0.90 TSHR (0.62) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL6856328 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996007633-A1 PHENYLACETIC ACID ALKYL ESTERS BASF AKTIENGESELLSCHAFT (DE) 1996-03-14 WO disclosed