Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056476 | 0.97 | F2 (0.39) | F2ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL9055904 | 0.93 | F2 (0.40) | F2ITGB3ITGAVITGA2BPRSS1 | |
| SCHEMBL9058407 | 0.92 | F2 (0.42) | F2ITGB3ITGAVITGA2BPRSS1 | |
| SCHEMBL9056591 | 0.87 | F2 (0.39) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9055274 | 0.85 | F2 (0.44) | F2PRSS1F10LMNAPLAT | |
| SCHEMBL9057565 | 0.85 | F2 (0.42) | F2PRSS1F10LMNAPLAT | |
| SCHEMBL9055877 | 0.85 | F2 (0.47) | F2PRSS1F10LMNAPLAT | |
| SCHEMBL9055170 | 0.85 | F2 (0.38) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9054878 | 0.84 | F2 (0.57) | F2PRSS1F10LMNAPLAT | |
| SCHEMBL9066880 | 0.83 | F2 (0.47) | F2PRSS1F10LMNAPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |