SCHEMBL9058485

SCHEMBL9058485

C=CCOC(=N)OCC=C

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
TSHR P16473 3/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11882266 0.87
SCHEMBL1883675 0.77
SCHEMBL5427510 0.77
Hydrochloric Acid SCHEMBL5820383 0.75
SCHEMBL7650901 0.73 CYP3A4 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL45115 0.73
SCHEMBL3794354 0.73
SCHEMBL4693125 0.73
SCHEMBL17870872 0.71
SCHEMBL7646236 0.71 CYP3A4 (0.39) CYP3A4TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3224390-B1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2019-06-12 EP claimed
US-20180347055-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2018-12-06 US claimed
EP-3224390-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES Covestro Deutschland AG (DE) 2017-10-04 EP claimed
WO-2016083475-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2016-06-02 WO claimed
EP-3224390-B1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2019-06-12 EP disclosed
US-20180347055-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2018-12-06 US disclosed
US-20180347055-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2018-12-06 US disclosed
EP-3224390-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES Covestro Deutschland AG (DE) 2017-10-04 EP disclosed
EP-3224390-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES Covestro Deutschland AG (DE) 2017-10-04 EP disclosed
WO-2016083475-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2016-06-02 WO disclosed
WO-2016083475-A1 ELECTROCHEMICAL SYNTHESIS OF DICARBAMATES COVESTRO DEUTSCHLAND AG (DE) 2016-06-02 WO disclosed
EP-0519868-B1 Preparation of dialkyl (N-cyanoimido)carbonates CIBA GEIGY AG (CH) 1996-08-21 EP disclosed
CN-1028753-C Preparation of dialkyl (N-cyanoimido) carbonates CIBA GEIGY AG (CH) 1995-06-07 CN disclosed
US-5208351-A PROCESS FOR THE PREPARATION OF N-CYANOIMIDOCARBONATES SKW TROSTBERG AKTIENGESELLSCHAFT (DE) 1993-05-04 US disclosed
CN-1067649-A The preparation of (N-cyanogen imido) dialkyl carbonate CIBA GEIGY AG (CH) 1993-01-06 CN disclosed
EP-0519868-A2 Preparation of dialkyl (N-cyanoimido)carbonates CIBA-GEIGY AG (CH) 1992-12-23 EP disclosed