Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GRM8 | O00222 | 2/20 | 0.58 |
| ▸ | GRM6 | O15303 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26934469 | 0.90 | GRM4 (0.54) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL31370260 | 0.84 | GRM4 (0.58) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL31231770 | 0.83 | GRM4 (0.50) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL27659968 | 0.78 | GRM4 (0.55) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL15057785 | 0.76 | — | — | |
| SCHEMBL15060220 | 0.76 | — | — | |
| SCHEMBL25492080 | 0.74 | GRM4 (0.58) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL25492047 | 0.74 | GRM4 (0.58) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL659587 | 0.74 | GRM4 (1.00) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL23833793 | 0.74 | GRM4 (0.58) | GRM4CYP1A2CYP2C19ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020010-A1 | COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC | ORIDIGM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |