SCHEMBL9058968

SCHEMBL9058968

CC(C)=CCCC(C)=CCNc1ccc(C(=O)O)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 10/20 0.51
TRPA1 O75762 2/20 0.43
ICMT O60725 1/20 0.43
GMNN O75496 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
CDK2 P24941 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6654122 1.00 TRPV1 (0.51) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL9059232 0.99 TRPV1 (0.50) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL9059233 0.99 TRPV1 (0.50) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL3600239 0.84 TRPV1 (0.53) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL3600241 0.84 TRPV1 (0.53) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL28570841 0.83 TRPV1 (0.56) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL8224018 0.83 TRPV1 (0.52) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL8224019 0.82 TRPV1 (0.55) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL4653741 0.80 TRPV1 (0.46) TRPV1TRPA1ICMTGMNNLMNA
SCHEMBL4653744 0.80 TRPV1 (0.46) TRPV1TRPA1ICMTGMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996017589-A1 METHOD OF SMOOTHING OR REMOVING WRINKLES AND METHOD OF STIMULATING COLLAGEN SYNTHESIS KAO CORPORATION (JP) 1996-06-13 WO disclosed