SCHEMBL9059

SCHEMBL9059

O=[C]OC(Cl)(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7900602 0.72
SCHEMBL1335384 0.69
SCHEMBL95053 0.67
SCHEMBL787873 0.63
SCHEMBL2153342 0.63
SCHEMBL3756514 0.63
SCHEMBL3749141 0.63
SCHEMBL1148842 0.63
SCHEMBL11174465 0.61
SCHEMBL5324638 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5863 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118302422-A Substituted N-cyanopyrrolidines having activity as USP30 inhibitors 特殊治疗有限公司 2024-07-05 CN claimed
EP-4157834-B1 N-(1-CYANO-PYRROLIDIN-3-YL)-5-(3-(TRIFLUOROMETHYL)PHENYL)OXAZOLE-2-CARBOXAMIDE DERIVATIVES AND THE CORRESPONDING OXADIAZOLE DERIVATIVES AS USP30 INHIBITORS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION MISSION THERAPEUTICS LTD (GB) 2024-07-03 EP claimed
CN-115215910-B Chitosan oligosaccharide synthesis method with controllable polymerization degree 山东京博农化科技股份有限公司 2024-06-18 CN claimed
CN-118005716-B Cytotoxin derivative and preparation method and application thereof 南京联宁生物制药有限公司 2024-06-11 CN claimed
EP-4373494-A1 METHODS FOR PREPARING BISPHOSPHOCINS Lakewood Amedex, Inc. (US) 2024-05-29 EP claimed
CN-118084988-A Polymerization monomer for preparing beta-1, 3 glucan and polymerization method 山东大学 2024-05-28 CN claimed
CN-118027116-A Pseudomonas aeruginosa O11 serotype O-antigen trisaccharide and synthesis method thereof 山东大学 2024-05-14 CN claimed
CN-118005716-A Cytotoxin derivative and preparation method and application thereof 南京联宁生物制药有限公司 2024-05-10 CN claimed
US-20240110887-A1 SENSOR DEVICE KABUSHIKI KAISHA TOSHIBA (JP) 2024-04-04 US claimed
CN-114341133-B Substituted cyanopyrrolidines having USP30 inhibitor activity 特殊治疗有限公司 2024-02-27 CN claimed
US-4053286-A ACYLATION MERCK & CO., INC. (US) 1977-10-11 US claimed
US-4048430-A Mercaptopseudotrisaccharides SMITHKLINE CORPORATION (US) 1977-09-13 US claimed
US-4044002-A ACYL BROMIDES AND A BROMINE SCAVENGER ELI LILLY AND COMPANY (US) 1977-08-23 US claimed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3997524-A Process for the manufacture of 6'-N-alkyl derivatives of sisomicin and verdamicin; novel intermediates useful therein, and novel 6'-N-alkylverdamicins prepared thereby SCHERING CORPORATION (US) 1976-12-14 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3963695-A Tetradeoxyneamine and derivatives thereof SMITHKLINE CORPORATION (US) 1976-06-15 US claimed
US-3960838-A Mercaptopseudodisaccharides SMITHKLINE CORPORATION (US) 1976-06-01 US claimed
US-3953422-A Deoxyglucose derivatives SMITHKLINE CORPORATION (US) 1976-04-27 US claimed