SCHEMBL9059526

SCHEMBL9059526

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nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
TDP1 Q9NUW8 2/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
GABRR1 P24046 2/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM1 P11229 1/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
TET2 Q6N021 3/20 0.36
KDM4A O75164 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28163011 0.92 SLC1A3 (0.42) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL28163012 0.92 SLC1A3 (0.42) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL16052820 0.92 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL14877096 0.92 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL2296713 0.92 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL28163010 0.92 SLC1A3 (0.42) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL2296715 0.92 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL22205227 0.92 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL22205225 0.92 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1
SCHEMBL183381 0.87 TP53 (0.41) TP53TDP1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996028488-A1 METHOD OF PRODUCING BIODEGRADABLE POLYURETHANE ESTERS BUNA SOW LEUNA OLEFINVERBUND GMBH (DE) 1996-09-19 WO disclosed