Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | GFER | P55789 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL420252 | 0.88 | HPGD (0.72) | MEN1KMT2AGFERALDH1A1HPGD | |
| SCHEMBL29750310 | 0.88 | MEN1 (1.00) | MEN1KMT2AGFERALDH1A1HPGD | |
| SCHEMBL2576382 | 0.86 | KDM4E (0.76) | MEN1KMT2AALDH1A1HPGDCYP3A4 | |
| SCHEMBL28693348 | 0.80 | KDM4E (0.72) | MEN1KMT2AALDH1A1HPGDCYP2C9 | |
| SCHEMBL24426075 | 0.80 | MEN1 (0.72) | MEN1KMT2AGFERALDH1A1HPGD | |
| SCHEMBL14970875 | 0.79 | CYP3A4 (1.00) | MEN1KMT2AGFERALDH1A1HPGD | |
| SCHEMBL14518623 | 0.79 | MEN1 (0.72) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6451951 | 0.79 | TACR3 (0.61) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16307495 | 0.79 | MAPT (0.74) | MEN1KMT2AALDH1A1HPGDCYP3A4 | |
| SCHEMBL19508618 | 0.79 | MEN1 (0.70) | MEN1KMT2AALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002509-A1 | QUINOLINE DERIVATIVES AS NK3 ANTAGONISTS | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1996-02-01 | — | — | WO | disclosed |