SCHEMBL9059724

SCHEMBL9059724

CCOC(=O)NC1CCCCC1=O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.47
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
NAAA Q02083 10/20 0.39
ASAH1 Q13510 1/20 0.39
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14809036 0.78 CA1 (0.44) CYP11B1CYP11B2KMT2A
SCHEMBL9932237 0.77 GAA (0.50) NFKB1NFKB2RELAKMT2A
SCHEMBL999679 0.77 GAA (0.50) NFKB1NFKB2RELAKMT2A
SCHEMBL25981811 0.77 GAA (0.50) NFKB1NFKB2RELAKMT2A
SCHEMBL1935629 0.77 MCL1 (0.42) KMT2A
SCHEMBL2792237 0.77 MCL1 (0.42) KMT2A
SCHEMBL760401 0.77 EPHX1 (0.59) NAAAASAH1KMT2A
SCHEMBL14534711 0.77 EPHX1 (0.59) NAAAASAH1KMT2A
SCHEMBL24565369 0.75 HTT (0.46) KMT2A
SCHEMBL6093270 0.75 HTT (0.46) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996028157-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING L-ETRABAMINE, USES THEREOF, AND METHODS FOR PREPARING SAME LABORATOIRES JACQUES LOGEAIS (FR) 1996-09-19 WO disclosed