Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668242 | 0.79 | SMN1; SMN2 (0.57) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL31162470 | 0.79 | SMN1; SMN2 (0.57) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL29444184 | 0.79 | TSHR (0.56) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL674136 | 0.79 | TSHR (0.56) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL31016399 | 0.77 | TSHR (0.54) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL29506761 | 0.77 | SMN1; SMN2 (0.65) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL2026918 | 0.77 | TSHR (0.54) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL325007 | 0.77 | SMN1; SMN2 (0.65) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL13689698 | 0.77 | MEN1 (0.59) | TSHRSMN1; SMN2CASP1MAPTKDM4E | |
| SCHEMBL19350065 | 0.77 | TSHR (0.54) | TSHRSMN1; SMN2CASP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8295661-A | — | — | None | — | — | JP | disclosed |
| JP-H08295661-A | AMIDE COMPOUND AND ITS USE | SUMITOMO CHEM CO LTD | 1996-11-12 | — | — | JP | disclosed |