Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL8836326 | 0.99 | PPARG (0.42) | PPARGPPARDS1PR5S1PR1CD274 | |
| SCHEMBL8836583 | 0.98 | PPARG (0.44) | PPARGPPARDS1PR5S1PR1CD274 | |
| SCHEMBL8836590 | 0.98 | PPARG (0.44) | PPARGPPARDS1PR5S1PR1CD274 | |
| SCHEMBL8876644 | 0.98 | PPARG (0.44) | PPARGPPARDS1PR5S1PR1CD274 | |
| SCHEMBL8484746 | 0.85 | PPARG (0.45) | PPARGPPARDS1PR5S1PR1CD274 | |
| Mandelic Acid SCHEMBL8955735 | 0.85 | PPARD (0.44) | PPARGPPARDS1PR5S1PR1CD274 | |
| SCHEMBL8876136 | 0.80 | MAOB (0.55) | PPARGPPARDCD274FFAR1MAOB | |
| SCHEMBL8875180 | 0.80 | MAOB (0.55) | PPARGPPARDCD274FFAR1MAOB | |
| SCHEMBL8877619 | 0.80 | MAOB (0.55) | PPARGPPARDCD274FFAR1MAOB | |
| SCHEMBL29435306 | 0.77 | PPARG (0.44) | PPARGPPARDS1PR5S1PR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996019438-A1 | AN ENANTIOSELECTIVE SYNTHESIS OF CERTAIN HYDROXYLAMINES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-27 | — | — | WO | disclosed |