Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060065 | 1.00 | KDM1A (0.40) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9060783 | 0.91 | KDM1A (0.40) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9060778 | 0.91 | KDM1A (0.40) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9060996 | 0.89 | KDM1A (0.38) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9061009 | 0.89 | KDM1A (0.38) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9061733 | 0.88 | KDM1A (0.38) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9061727 | 0.88 | KDM1A (0.38) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9062414 | 0.87 | KDM1A (0.37) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9062450 | 0.87 | KDM1A (0.37) | KDM1ARCOR1TSHRLIPEEPHX2 | |
| SCHEMBL9062409 | 0.87 | KDM1A (0.37) | KDM1ARCOR1TSHRLIPEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5324449-A | Substituted phenyl trifluoromethyl ethers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-28 | — | — | US | disclosed |