Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HTR6 | P50406 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | HTR1D | P28221 | 2/20 | 0.61 |
| ▸ | HTR1B | P28222 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.61 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742359 | 0.86 | HTR2A (0.61) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL6159296 | 0.86 | HTR2A (0.61) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL4656420 | 0.85 | MEN1 (0.62) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL17732258 | 0.82 | MEN1 (0.58) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL6156912 | 0.82 | MEN1 (0.58) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL11374725 | 0.82 | MEN1 (0.58) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL17732259 | 0.82 | MEN1 (0.58) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL6803427 | 0.82 | MEN1 (0.58) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL10382799 | 0.81 | MEN1 (0.67) | HTR2ACYP3A4HTR6HTR2CCYP2D6 | |
| SCHEMBL1519983 | 0.80 | HTR2A (0.54) | HTR2ACYP3A4HTR6HTR2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8157471-A | — | — | None | — | — | JP | disclosed |
| JP-H08157471-A | 3-(BENZENESULFONAMIDOALKYL)INDOLE DERIVATIVE | TERUMO CORP | 1996-06-18 | — | — | JP | disclosed |