Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 4/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14924284 | 0.91 | ESR2 (0.52) | ESR2IDO1LMNAALDH1A1HRH3 | |
| SCHEMBL9060709 | 0.86 | ESR2 (0.47) | ESR2IDO1LMNAALDH1A1HRH3 | |
| SCHEMBL13480380 | 0.86 | ESR2 (0.47) | ESR2IDO1LMNAALDH1A1HRH3 | |
| SCHEMBL9061934 | 0.86 | ESR2 (0.47) | ESR2IDO1LMNAALDH1A1HRH3 | |
| SCHEMBL9061943 | 0.86 | ESR2 (0.47) | ESR2IDO1LMNAALDH1A1HRH3 | |
| SCHEMBL9060161 | 0.85 | ACACB (0.45) | ACACBIDO1LMNA | |
| SCHEMBL9061790 | 0.82 | CYP2C9 (0.45) | ACACBESR2IDO1LMNAALDH1A1 | |
| SCHEMBL9062362 | 0.82 | ESR2 (0.44) | ACACBESR2IDO1LMNAALDH1A1 | |
| SCHEMBL9062365 | 0.82 | ESR2 (0.44) | ACACBESR2IDO1LMNAALDH1A1 | |
| SCHEMBL9061110 | 0.82 | ESR2 (0.44) | ESR2IDO1LMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5389292-A | Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |